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EPC Evidence Reports

Topics In Progress
Completed Reports:
Clinical / Health Care Services / Technical
Topic Index: A-Z
List of Reports by Number
Archived Reports

Completed Reports

Clinical

Cancer and Blood Disorders

Adnexal Mass (February 2006)
Abstract / Evidence Report

Adrenal Mass, Clinically Inapparent (February 2002)
Abstract / Summary / Evidence Report

Anemia, Managing with Epoetin and Darbepoetin (May 2006)
Comparative Evidence Review

Anemia in Oncology, Use of Epoetin (March 2001)
Abstract / Summary / Evidence Report

Breast Abnormalities, Noninvasive Diagnostic Tests (February 2006)
Comparative Evidence Review

Breast Abnormalities, Diagnosis and Management (April 2001)
Abstract / Summary / Evidence Report

Breast Cancer Care in Women, Measuring Quality (September 2004)
Abstract / Summary / Evidence Report

Breast Cancer Outcomes, Gene Expression Profiling Tests (January 2008)
Abstract / Evidence Report

Cancer Care Quality Measures, Colorectal Cancer (May 2006)
Abstract / Evidence Report

Cancer Care Quality Measures, Symptoms and End-of-Life (May 2006)
Abstract / Evidence Report

Cancer Clinical Trials, Recruitment of Underrepresented Populations (June 2005)
Abstract / Summary / Evidence Report

Cancer Control Interventions, Diffusion and Dissemination (May 2003)
Abstract / Summary / Evidence Report

Cancer Family History, Collection and Use in Primary Care (October 2007)
Abstract / Evidence Report

Cancer Pain, Management (January 2001)
Abstract / Summary / Evidence Report: Volume I, Volume II

Cancer Risk, Dietary Behavior (November 2000)
Abstract / Summary / Evidence Report

Cancer Symptoms, Management (July 2002)
Abstract / Summary / Evidence Report

Hereditary Nonpolyposis Colorectal Cancer (May 2007)
Abstract / Evidence Report

Hydroxyurea for the Treatment of Sickle Cell Disease (February 2008)
Abstract / Evidence Report

Immuno-Augmentation Therapy and Naltrexone for Cancer Treatment (April 2003)
Abstract / Summary / Evidence Report

Impact of Cancer-Related Decision Aids (July 2002)
Abstract / Summary / Evidence Report

Ovarian Cancer, Genomic Tests for Detection and Management (October 2006)
Abstract / Evidence Report

Physical Activity, General Population and Cancer Patients and Survivors (June 2004)
Abstract / Summary / Evidence Report

Prostate Cancer, Therapies for Clinically Localized (February 2008)
Comparative Evidence Review

Small Cell Lung Cancer, Management (July 2006)
Abstract / Evidence Report

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Complementary and Alternative Care

Ayurvedic Treatments for Diabetes Mellitus (June 2001)
Abstract / Summary / Evidence Report

Meditation Practices for Health (June 2007)
Abstract / Evidence Report

Mind-Body Interventions, Gastrointestinal Conditions (March 2001)
Abstract / Summary / Evidence Report / Selected Publications

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Dietary Supplements

Antioxidant Supplements, Cancer Prevention and Treatment (October 2003)
Abstract / Summary / Evidence Report

Antioxidant Supplements, Cardiovascular Disease Prevention and Treatment (July 2003)
Abstract / Summary / Evidence Report

B Vitamins and Berries and Age-Related Neurodegenerative Disorders (April 2006)
Abstract / Evidence Report

Ephedra and Ephedrine for Weight Loss and Athletic Performance Enhancement (March 2003)
Abstract / Summary / Evidence Report

Garlic, Effects (October 2000)
Abstract / Summary / Evidence Report

Melatonin, Treatment of Sleep Disorders (November 2004)
Abstract / Summary / Evidence Report

Milk Thistle Effects (September 2000)
Abstract / Summary / Evidence Report

Multivitamin/Mineral Supplements, Chronic Disease Prevention (May 2006)
Abstract / Evidence Report

Omega-3 Fatty Acids, Effects on Arrhythmogenic Mechanisms in Culture Studies (March 2004)
Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Asthma (March 2004)
Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Cancer (February 2005)
Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Cardiovascular Disease (March 2004)
Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Cardiovascular Risk Factors (March 2004)
Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Child and Maternal Health (August 2005)
Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Cognitive Functions (February 2005)
Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Eye Health (July 2005)
Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects in Type II Diabetes, Rheumatoid Arthritis, and Other Diseases (March 2004)
Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Mental Health (July 2005)
Abstract / Summary / Evidence Report

Omega-3 Fatty Acids, Effects on Organ Transplantation (February 2005)
Abstract / Summary / Evidence Report

S-Adenosyl-L-Methionine (SAMe) for Depression, Osteoarthritis, and Liver Disease (August 2002)
Abstract / Summary / Evidence Report

Soy, Effects on Health Outcomes (August 2005)
Abstract / Summary / Evidence Report

Vitamin D, Effectiveness and Safety in Bone Health (August 2007)
Abstract / Evidence Report

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Ear, Nose, and Throat Conditions

Rhinitis, Allergic and Nonallergic (May 2002)
Abstract / Summary / Evidence Report

Rhinitis, Allergic, in the Working-Age Population (February 2003)
Abstract / Summary / Evidence Report

Sinusitis, Acute Bacterial—Update (June 2005)
Abstract / Summary / Evidence Report

Speech/Language Disorders, Criteria for Determining Disability (January 2002)
Abstract / Summary / Evidence Report

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Eye Conditions

Cataract and Glaucoma, Surgical Treatment (September 2000)
Abstract / Summary / Evidence Report

Cataract Surgery, Anesthesia Management (July 2000)
Abstract / Summary / Evidence Report: Volume I, Volume II / Selected Publications

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Heart and Vascular Diseases

Abdominal Aortic Aneurysm, Endovascular and Open Surgical Repairs (August 2006)
Abstract / Evidence Report

Angina, Unstable (August 2000)
Abstract / Summary / Evidence Report / Selected Publications

Arterial Bypass, Percutaneous Coronary Interventions and Coronary Artery Bypass Grafting (October 2007)
Comparative Evidence Review

Atrial Fibrillation, New Onset (May 2000)
Abstract / Summary / Evidence Report / Selected Publications

Blood Pressure Monitoring, Ambulatory (November 2002)
Abstract / Summary / Evidence Report

Carbohydrate and Lipid Disorders in Persons with Spinal Cord Injury (January 2008)
Abstract / Evidence Report

Cardiac Ischemia, Acute, Emergency Department Technologies (September 2000)
Abstract / Summary / Evidence Report / Selected Publications

Cardiovascular Effects of Epinephrine (March 2002)
Abstract / Summary / Evidence Report

Coronary Heart Disease in Women, Selected Topics (May 2003)
Abstract / Summary / Evidence Report

Coronary Heart Disease in Women, Systematic Review (May 2003)
Abstract / Summary / Evidence Report

Deep Venous Thrombosis and Pulmonary Embolism (January 2003)
Abstract / Summary / Evidence Report

Heart Failure, Cardiac Resynchronization Therapy (November 2004)
Abstract / Summary / Evidence Report

Heart Failure Diagnosis and Prognosis, Testing for BNP and NT-proBNP (September 2006)
Abstract / Evidence Report

Heart Failure and Left Ventricular Systolic Dysfunction, Pharmacologic Management (July 2003)
Abstract / Summary / Evidence Report

Hypertension, Treatment with Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Antagonists (ARBs) (November 2007)
Comparative Evidence Review

Left Ventricular Systolic Dysfunction, Cardiac Resynchronization Therapy & Implantable Cardiac Defibrillators (June 2007)
Abstract / Evidence Report

Physical Activity, General Population and Cancer Patients and Survivors (June 2004)
Abstract / Summary / Evidence Report

Post-Myocardial Infarction Depression (May 2005)
Abstract / Summary / Evidence Report

Renal Artery Stenosis, Management Strategies (October 2006)
Comparative Evidence Review

Renal Artery Stenosis, Management Strategies (2007 Update)
Comparative Evidence Review

Venous Thromboembolism, Prevention After Injury (August 2000)
Abstract / Summary / Evidence Report

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Infectious Diseases

Antiretroviral (ARV) Drug Resistance in the Developing World (September 2007)
Abstract / Evidence Report

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Kidney Conditions

Chronic Renal Failure, Determinants of Disability (May 2000)
Abstract / Summary / Evidence Report / Selected Publications

Chronic Renal Failure, Use of Epoetin for Anemia (March 2001)
Abstract / Summary / Evidence Report

Fecal and Urinary Incontinence in Adults, Prevention (December 2007)
Abstract / Evidence Report

Solid Organ Transplant, Monitoring Mycophenolic Acid (February 2008)
Abstract / Evidence Report

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Lung Conditions

Asthma, Chronic (September 2001)
Abstract / Summary / Evidence Report

Asthma, Work-Related (October 2005)
Abstract / Summary / Evidence Report

Chronic Obstructive Pulmonary Disease, Acute Exacerbations (September 2000)
Abstract / Summary / Evidence Report / Selected Publications

Chronic Obstructive Pulmonary Disease, Spirometry (August 2005)
Abstract / Summary / Evidence Report

Mechanical Ventilation, Criteria for Weaning (June 2000)
Abstract / Summary / Evidence Report / Selected Publications

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Mental Health Conditions and Substance Abuse

Adult Depression, Treatment with Second-Generation Antidepressants (January 2007)
Comparative Evidence Review

Adults with Non-Psychotic Depression Treated with SSRIs, CYP450 Testing (January 2007)
Abstract / Evidence Report

Atypical Antipsychotics, Off-Label Use (January 2007)
Comparative Evidence Review

Attention-Deficit/Hyperactivity Disorder, Diagnosis (October 1999)
Clinical Focus / Summary

Attention-Deficit/Hyperactivity Disorder, Treatment (November 1999)
Abstract / Summary / Evidence Report / Selected Publications

Alcohol Dependence, Pharmacotherapy (January 1999)
Abstract / Summary / Evidence Report / Selected Publications

Depression, Perinatal (February 2005)
Abstract / Summary / Evidence Report

Depression, Post-Myocardial Infarction (May 2005)
Abstract / Summary / Evidence Report

Eating Disorders, Management (April 2006)
Abstract / Evidence Report

Tobacco Use: Prevention, Cessation, and Control (June 2006)
Abstract / Evidence Report

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Metabolic, Nutritional, and Endocrine Conditions

Diabetes Education for Children (April 2008)
Abstract / Evidence Report

Diabetes Mellitus, Islet Transplantation in Patients (July 2004)
Abstract / Summary / Evidence Report

Diabetes Mellitus, Use of Glycated Hemoglobin and Microalbuminuria (July 2003)
Abstract / Summary / Evidence Report

Diabetes, Oral Medications ((July 2007)
Comparative Evidence Review

Gestational Diabetes (March 2008)
Abstract / Evidence Report

Impaired Glucose Tolerance and Fasting Glucose, Diagnosis, Prognosis, and Therapy (September 2005)
Abstract / Summary/ Evidence Report

Obesity, Pharmacological and Surgical Treatment (July 2004)
Abstract / Summary / Evidence Report / Clinician's Aid

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Musculoskeletal Disorders

Chronic Fatigue Syndrome, Defining and Managing (September 2001)
Abstract / Summary / Evidence Report

Chronic Fatigue Syndrome, Disability (December 2002)
Abstract / Summary / Evidence Report

Osteoarthritis, Treatment and Safety of Analgesics (September 2006)
Comparative Evidence Review

Osteoarthritis of the Knee (October 2007)
Abstract / Evidence Report

Osteoporosis, Treatments to Prevent Fractures (December 2007)
Comparative Evidence Review

Osteoporosis in Postmenopausal Women (February 2001)
Abstract / Summary / Evidence Report

Rheumatoid and Psoriatic Arthritis, Drug Therapy (November 2007)
Comparative Evidence Review

Total Knee Replacement (December 2003)
Abstract / Summary / Evidence Report

Worker-Related Musculoskeletal Disorders (October 2002)
Abstract / Summary / Evidence Report

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Nerve and Brain Conditions

Age-Related Neurodegenerative Disorders, B Vitamins and Berries (April 2006)
Abstract / Evidence Report

Dementia, Pharmacological Treatment (April 2004)
Abstract / Summary / Evidence Report

Epilepsy, Management of Newly Diagnosed Patients (February 2001)
Abstract / Summary /

Headache, Treatment (February 1999)
Overview

Hyperbaric Oxygen Therapy (September 2003)
Abstract / Summary / Evidence Report

Insomnia, Manifestations and Management (June 2005)
Abstract / Summary / Evidence Report

Multiple Sclerosis, Criteria to Determine Disability (May 2004)
Abstract / Summary / Evidence Report

Parkinson's Disease, Diagnosis and Treatment (June 2003)
Abstract / Summary / Evidence Report

Spinal Cord Injury, Neurogenic/Neuropathic Pain (September 2001)
Abstract / Summary / Evidence Report

Spinal Cord Injury, Pulmonary Disease (June 2001)
Abstract / Summary / Evidence Report

Spinal Cord Injury, Sexuality and Reproductive Health (December 2004)
Abstract / Summary / Evidence Report

Spinal Stenosis, Degenerative Lumbar Treatment (March 2001)
Abstract / Summary / Evidence Report: Volume I, Volume II

Stroke, Evaluation and Treatment (July 2005)
Abstract / Summary / Evidence Report

Stroke, Management Effectiveness (July 2002)
Abstract / Summary / Evidence Report

Treatment-Resistant Epilepsy (April 2003)
Abstract / Summary / Evidence Report

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Obstetric and Gynecologic Conditions

Adnexal Mass (February 2006)
Abstract / Evidence Report

Breastfeeding, Maternal and Infant Health Outcomes (April 2007)
Abstract / Evidence Report

Cesarean Delivery on Maternal Request (March 2006)
Abstract / Evidence Report

Effectiveness of Assisted Reproductive Technology (May 2008)
Abstract / Evidence Report

Episiotomy Use in Obstetrical Care (May 2005)
Abstract / Summary/ Evidence Report

Hypertension During Pregnancy (August 2000)
Abstract / Summary / Evidence Report

Maternal Weight Gain, Outcomes (May 2008)
Abstract / Evidence Report

Menopause-Related Symptoms, Management (March 2005)
Abstract / Summary / Evidence Report

Ovarian Cancer, Genomic Tests for Detection and Management (October 2006)
Abstract / Evidence Report

Perinatal Depression: Prevalence and Screening (February 2005)
Abstract / Summary / Evidence Report

Prolonged Pregnancy (March 2002)
Abstract / Summary / Evidence Report

Uterine Fibroids—Update (July 2007)
Abstract / Evidence Report
Original Evidence Report: Volume I, Volume II (January 2001)

Vaginal Birth After Cesarean (March 2003)
Abstract / Summary / Evidence Report

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Oral and Gastrointestinal Disorders

Celiac Disease (June 2004)
Abstract / Summary / Evidence Report

Dental Caries, Diagnosis and Management (February 2001)
Abstract / Summary / Evidence Report

Dental Patients Who Are HIV Positive (February 2001)
Abstract / Summary / Evidence Report

Endoscopic Retrograde Cholangiopancreatography (ERCP) (March 2001)
Abstract / Summary / Evidence Report

Gastroesophageal Reflux Disease, Management Strategies (December 2005)
Comparative Effectiveness Review

Hepatitis C (June 2002)
Abstract / Summary / Evidence Report

Periodontitis, Scaling and Root Planing Therapy (January 2004)
Abstract / Summary / Evidence Report

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Pathology

Autopsy (October 2002)
Abstract / Summary / Evidence Report

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Pediatric Conditions

Asthma, Chronic (September 2001)
Abstract / Summary / Evidence Report

Breastfeeding, Maternal and Infant Health Outcomes (April 2007)
Abstract / Evidence Report

Bronchiolitis in Infants and Children (January 2003)
Abstract / Summary / Evidence Report

Failure to Thrive, Determining Disability in Infants and Children (March 2003)
Abstract / Summary / Evidence Report

Low Birth Weight, Determining Disability in Infants and Children (March 2003)
Abstract / Summary / Evidence Report

Neonatal Hyperbilirubinemia (November 2002)
Abstract / Summary / Evidence Report

Otitis Media, Acute (June 2000)
Abstract / Summary / Evidence Report / Selected Publications

Otitis Media with Effusion, Diagnosis (June 2002)
Abstract / Summary / Evidence Report: Volume I, Volume II

Pediatric Anthrax, Bioterrorism Preparedness (August 2006)
Abstract / Evidence Report

Short Stature, Determining Disability in Infants and Children (March 2003)
Abstract / Summary / Evidence Report

Toilet Training, Effectiveness of Different Methods (December 2006)
Abstract / Evidence Report

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Skin Conditions

Acne, Management (March 2001)
Abstract / Summary / Evidence Report: Volume I, Volume II

Heparin, Uses Treat Burn Injury (December 2006)
Abstract / Evidence Report

Wound Healing, Laser Treatment and Vacuum-Assisted Closure (December 2004)
Abstract / Summary / Evidence Report

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Health Care Services

Bioterrorism

Bioterrorism Preparedness, Training of Clinicians (December 2001)
Abstract / Summary / Evidence Report

Bioterrorism Preparedness, Information Technology (June 2002)
Abstract / Summary / Evidence Report

Bioterrorism Preparedness, Regionalization (April 2004)
Abstract / Summary / Evidence Report

Mass Casualty Incident, Training Hospital Staff to Respond (April 2004)
Abstract / Summary / Evidence Report

Pediatric Anthrax, Bioterrorism Preparedness (August 2006)
Abstract / Evidence Report

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Financing and Economic Incentives

Medicare Expenditures for Physicians' Services (October 2003)
Clinical Focus

Preventive Care, Economic Incentives (August 2004)
Abstract / Summary / Evidence Report

Quality-based Purchasing, Support Strategies (July 2004)
Abstract / Summary / Technical Review

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Information Technology

Health Information Technology, Costs and Benefits (April 2006)
Abstract / Evidence Report

Telemedicine for the Medicare Population—Update (January 2006)
Abstract / Evidence Report
Original Evidence Report (July 2001)

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Quality Improvement and Patient Safety

Children With Special Health Care Needs, Care Coordination Strategies
Abstract / Technical Review

Closing the Quality Gap
Vol. 1: Series Overview and Methodology (August 2004)
Abstract / Fact Sheet / Technical Review
Vol. 2: Diabetes Mellitus (September 2004)
Abstract / Technical Review
Vol. 3: Hypertension Care (January 2005)
Abstract / Technical Review
Vol. 4: Antibiotic Prescribing Behavior (January 2006)
Abstract / Technical Review
Vol. 5: Asthma Care (January 2007)
Abstract / Technical Review
Vol. 6: Healthcare-Associated Infections (January 2007)
Abstract / Technical Review
Vol. 7: Care Coordination (June 2007)
Abstract / Technical Review

Continuing Medical Education, Effectiveness (February 2007)
Abstract / Evidence Report

End-of-Life Care and Outcomes (November 2004)
Abstract / Summary / Evidence Report

Literacy and Health Outcomes (January 2004)
Abstract / Summary / Evidence Report

Minority Healthcare Quality, Improvement Strategies (January 2004)
Abstract / Summary / Evidence Report

Nurse Staffing and Quality of Patient Care (March 2007)
Abstract

Patient Safety Indicators: Hospital Data (August 2002)
Abstract / Technical Review

Patient Safety Practices, Making Health Care Safer (July 2001)
Abstract/ Summary / Evidence Report (HSTAT; HTML)

Patient Safety, Effects of Working Conditions (March 2003)
Abstract / Summary / Evidence Report

Periodic Health Evaluation, Value (April 2006)
Abstract / Evidence Report

Refinement of the HCUP Quality Indicators (May 2001)
Summary / Technical Review

Violence Prevention in Adolescents (October 2004)
Abstract / Summary / Evidence Report

Technical

Methodology

Community-Based Participatory Research (August 2004)
Abstract / Summary / Evidence Report

Current Validity of AHRQ Clinical Practice Guidelines (September 2002)
Abstract / Technical Review

Empirical Evaluation, Association Between Methodological Shortcomings and Estimates of Adverse Events (October 2006)
Abstract / Technical Review

Health Benefit Design, Consumer-Oriented Strategies for Improving (July 2007)
Abstract / Technical Review

Meta-regression Approaches: What, Why, When, and How? (March 2004)
Abstract / Technical Review

Rating Systems for Strength of Scientific Evidence (March 2002)
Abstract / Summary / Evidence Report / Fact Sheet / Selected Publications

Statement of Work for Technical Analysis, Methodology (January 2006)
Abstract / Technical Review

Systematic Reviews, Criteria for Distinguishing Effectiveness From Efficacy Trials (April 2006)
Abstract / Technical Review

Systematic Reviews, Updating (September 2007)
Abstract / Technical Review